PositiveID

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Molecular Diagnostics

Molecular Diagnostics

PositiveID, through its wholly owned Microfluidic Systems ("MFS") subsidiary, develops biological detection and diagnostics systems, including its M-BAND and Firefly Dx technologies. MFS began developing complex microfluidic systems to perform sample processing and purification for the Defense Advanced Projects Agency (DARPA). It then developed a similar system, including a thermal cycler for polymerase chain reaction (PCR) analysis for the US Army's Edgewood Chemical and Biological Command (ECBC). PositiveID's microfluidic technology replaces robotics and manual processes used in existing systems with integrated microfluidics in a closed, automated system, which reduces cost, increases reliability and enhances the effectiveness of sample processing.

PositiveID is focused primarily on its M-BAND airborne biot-hreat detector, which was developed under contract with the U.S. Department of Homeland Security ("DHS") Science & Technology directorate, and its Firefly Dx system, which is designed to deliver molecular diagnostic results from a sample in less than 30 minutes at the point-of-need, using a portable, handheld system.

The Company's M-BAND detection system continuously and autonomously analyzes air samples for the detection of pathogenic bacteria, viruses, and toxins for up to 30 days. Results from individual M-BAND instruments are reported via a secure wireless network in real time to give an accurate and up-to-date status of field conditions. M-BAND performs high specificity detection for up to six organisms on the Centers for Disease Control's category A and B select agents list.

The goal of the Company's Firefly Dx is to enable accurate diagnostics leading to more rapid and effective treatment than what is currently available with existing systems. Firefly is being developed further for a broad range of biological detection situations for applications including military, agricultural and healthcare. The system has already demonstrated the ability to detect and identify other common pathogens and diseases such as various strains of influenza, E. coli, methicillin-resistant staphylococcus aureus ("MRSA") and human papilloma virus ("HPV").

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